The slightest changes in almost any of the basic parameters of nature would have led to a universe without stable stars or without stars at all.
I recently came across a nice little video which seems to prove that π = 0. Each step seems reasonable.
“With all our advanced technology, we are not close to producing human-engineered self-replicating machines.”
Since there were no natural causes before nature came into existence, science cannot ever hope to explain this beginning. That is, if ID is excluded.
Carl Sagan famously said, “I believe that the extraordinary should be pursued. But extraordinary claims require extraordinary evidence.”